Research progress of the detection methods of di(2-ethyl hexyl) adipate

Di(2-ethyl hexyl) adipate (DEHA) has been widely used as a plasticizer. As a kind of biological endocrine interferon, its long-term use in large quantities would cause adverse effects on human beings and the environment. The detection methods of DEHA were reviewed, including the pretreatment technologies and detection technologies. The pretreatment technologies mainly included Soxhlet extraction, ultrasonic extraction, isotope dilution, top air extraction, liquid-liquid extraction, solid phase micro extraction, and microwave extraction methods, etc. The detection techniques mainly included spectral analysis, gas chromatography, liquid chromatography and their combined analysis methods, etc. The principles, characteristics and applications of different detection technologies were summarized and compared. It was proposed that subsequent studies could be carried out from the aspects of selecting the types of extractive agents for liquid-liquid extraction, combining extraction technologies such as ultrasound, improving DEHA detection ability in complex sample systems, and developing portable intelligent detection instruments.