Abstract: At present, China is confronted with more complex and severe environmental problems, and the government attaches great importance to the development of environmental protection industry. The environmental protection industry and industrial clusters in China are facing not only great opportunities for development, but also a series of problems. The development background of environmental protection industrial parks in China was introduced, the relevant national policy documents of environmental protection industry were sorted out, the current situation and regional distribution of major environmental protection industrial parks in China was expounded, and their regional differences were analyzed. At last, the main difficulties in the development of environmental protection industrial parks were summarized from the aspects of policy, technology, capital and regional development, and the corresponding suggestions were put forward to promote the development of environmental protection industrial parks more healthily and rapidly in China.