Abstract: Sedum plumbizincicola, a hyperaccumulator, has been widely used in the remediation of cadmium and zinc polluted soils, but the treatment of the crop liquor which contains heavy metals after squeeze and dehydration of harvest biomass is an urgent problem to be solved. Choosing acidic and neutral soils, a pot experiment was conducted to return different doses of liquor to two types of soils and to grow Sedum plumbizincicola. The dynamic changes of soil pH, dissoluble organic carbon (DOC), CaCl₂ extractable Cd and Zn (CaCl₂-Cd/Zn), as well as plant growth and heavy metal reabsorption were monitored. The results showed that the pH increased in acid soil but decreased in neutral soil, and the DOC concentration of both soils increased significantly on 7 and 30 d after the addition of liquor, while the soil DOC concentration and pH were closed to the controlled soil in the middle and late growth stages. The CaCl₂-Cd/Zn concentrations in acid soil treated with liquor increased gradually with growing time, and reached maximum on 105 d, while those in neutral soil showed a gradual decline. The liquor treatment inhibited the growth of Sedum plumbizincicola with reduced biomass, but increased the concentration of Cd in the shoots. With 100 mL/kg liquor treatment of acid soil, Cd and Zn accumulation in Sedum plumbizincicola shoot was higher than the input by addition of liquor, and the soil Cd and Zn concentrations after remediation were lower than soil initial values before liquor addition. Consequently, suitable dosage of liquor returning to the acid soil and planting Sedum plumbizincicola could remove Cd and Zn input by liquor again and achieve the dual purpose of liquor treatment and soil remediation.