Abstract: China is in a period of economic transformation and rapid development. Coordinated emission reduction of carbon dioxide and air pollutants is a challenge for economic and social development on the one side, and on the other side it is also an important opportunity to promote the green transformation of economic structure, accelerate the formation of green production mode and lifestyle, and boost high-quality development. Thus a comprehensive understanding of the air pollution and carbon dioxide reduction and economic development levels in various regions of China will be helpful for national and local governments to formulate policies related to "air pollution and carbon dioxide reduction" according to local conditions. Therefore, an "air pollution reduction-carbon dioxide reduction-economic development" comprehensive evaluation index system was constructed, and energy economy, pollutants and carbon dioxide emission data of 30 provinces/municipalities/autonomous regions in 2016 and 2018 were selected to make the comprehensive evaluation of the pollution reduction, carbon dioxide reduction and economic indicators of various regions using the grey correlation degree method, and the development status of various indicators was analyzed. In addition, the coordination of the three indicators in each region was analyzed, through the calculation of the binary coupling coordination degree and ternary coupling coordination degree of indicators. Based on the evaluation index scores and the coordination degree data of various regions, suggestions on air pollution and carbon dioxide reduction and regional economic development were put forward according to local conditions.