Abstract: Taking Wengyuan County in the mountainous area of northern Guangdong Province as an example, the authoritative research data sources in the fields of water resources, water hazards and water environment were adopted, combined with data on county topography, hydrology, ecological protection, land status survey, measured water quality sampling, etc., as well as related planning and standards. By using the methods of Euclidean distance buffer for water source combined with conservation capacity calculation, Bluespot model simulation and water environment load calculation, the regional water resources, water hazard and water environment security pattern were calculated and analyzed. On this basis, a comprehensive water security pattern under regional multi-perspectives was constructed. The analysis results showed that the security patterns of water resources, water hazards and water environment in Wengyuan County were closely related to the important water systems and related protected areas and landforms, the location of the upper, middle and lower reaches of Wengjiang River system and the surrounding intensity of human activities, and the pollution status of the water bodies, respectively. The low security areas in the comprehensive water security pattern of Wengyuan County were mainly distributed in ecologically sensitive and fragile areas such as drinking water sources, nature reserves, important water system corridors and water conservation areas and surrounding areas; the medium security areas were mainly distributed in the buffer zone of the low security ecologically sensitive and fragile area, including the adjacent affected area; the high security areas were mainly distributed in the periphery of the medium security buffer zone and its adjacent affected areas. In the comprehensive water security pattern of Wengyuan County, there was a small area conflict control area between the sensitive and fragile low security area and the construction land and permanent basic farmland protection area. However, it had a high degree of agreement with the redline of ecological conservation and the management space of soil and water conservation, which showed that the research results were in good agreement with the space of land management, related protection planning and practical management.