Abstract: A contrastive analysis of the CO column density data derived from Atmospheric InfraRed Sounder (AIRS) observations and the CO hourly concentration monitoring data in September 2010 was analyzed. The results showed that the two series of data were synchronous in time, with relative coefficient of 0.63(α=0.05), and thus the data from AIRS could reflect the surface CO pollution. The spatial and temporal distribution of CO in China during 2004-2010 was investigated by using the remote sensing data. It was found that the average CO column density order from heavy to light was North China, Yangtze River Delta, Central China, Pearl River Delta, Northeast China, Sichuan and Xinjiang. The peeks were reached in March or April and the column density was stable during the seven years. The CO column density distribution had the characteristic of distinct converging belt. Combined with the weather data, the results revealed that the uniform pressure fields covered in the center and rear of anticyclones were the main background fields to form distinct converging belts.