Abstract: According to Regulation on Environmental Management of New Chemical Substances, the chemicals testing laboratories which provided test data for new chemicals should be noticed by the Ministry of Environmental Protection (MEP), and also need to accept the supervision and inspection from MEP. By referring to the basic international GLP principles and experience in the practice of other GLP certification in China and combining with the inspection experience carried out by MEP and the situation of chemicals testing laboratories, current status and existing problems of chemicals testing laboratory management were discussed, which would provide new management ideas for promoting the chemicals laboratory system establishment.