Abstract: By analyzing characteristics of high-speed railway noise source and the propagation of acoustic because of sound barrier and on the basis of Cadna/A noise calculation mode, the high-speed railway noise prediction model based on Cadna/A software was established. The Cadna/A model was validated and corrected according to noise source strength data of Germany and China’s measurement as well as the noise projection models, and the noise prediction results consistent with the current calculating specifications obtained. Finally, according to characteristics of railway noise barriers, the Cadna/A model of railway noise barrier was established and the differences between calculated results and measurement results were little. The results show that the Cadna/A software is suitable for the environmental impact of high-speed railway noise prediction as long as appropriate validating amendments are made for the model parameters. Meanwhile, the model of railway noise barrier based on Cadna/A software can be used to guide the optimization of noise barrier design.