Abstract: Abstract: According to the research progress on industrial distribution ecological suitability, ecological suitability assessment of industrial layout should be based on the influence factors of industrial distribution, and focus on the impact of economic development, resource consumption, and pollution discharge. A 5-level ecological suitability evaluation index system was then constructed, and Tieling City was chosen as an example to evaluate its water ecological suitability of industrial distribution. Results showed that Diaobingshan City, Kaiyuan City and Tieling County had a relatively higher ecological suitability of industrial layout. The natural resources and environmental effect factor, and economic effect factor, were the primary influence factors of Tieling’s industrial distribution ecological suitability. Optimization strategy for Tieling’s industrial distribution was concluded from the aspects of industrial structure optimization, coordination between industrial layout, and water resources. The strategy could help Tieling’s ecological civilization construction, and promote its coordinated development of economy and society.