Abstract: The two most common PFCs pollutants found in nature were perfluorooctane sulfonate (PFOS) and perfluorooctane acid (PFOA). The recommendations of environmental safety thresholds of PFOS and PFOA were reviewed at home and abroad. Based on the pollution status of PFOS and PFOA in some basins and typical areas in China, the problems of the ecological risk management of PFCs in China were analyzed. Some suggestions were proposed, including formulating the PFOS and PFOA environmental quality criteria/standards, strengthening the ecological risk assessment of typical regional PFCs, and enhancing the material substitutes monitoring, ecological toxicity supervision and substitutes risk prevention and control, etc.