Abstract: In order to investigate whether spraying foliar fertilizer can relieve the toxic effect of heavy metals on rice, and using the rice varieties of Xiangwanxian 17 and Wuyou 369 as materials, the effects of multi-foliar fertilizers on seedling growth and the accumulation of Cd in shoots and roots parts of rice under different soil Cd concentrations were determined by pot experiments. The results show that spraying multi-foliar fertilizers can not only promote the growth of plant height and dry weight of the two rice seedlings, but also effectively inhibit the accumulation of Cd in the shoots of rice. The inhibitory effect on Xiangwanxian 17 is better than that of Wuyou 369. It is indicated that the regulation effect of multi-nutrients foliar fertilizers on rice Cd accumulation may be related to the difference of rice varieties and soil Cd concentrations.