Abstract: According to the characteristics of strong acidity, high chloride ion concentration and high conductivity of disperse dyes wastewater, the ratio of COD removal rate to energy consumption (CRR/EC) was established to evaluate the effect of electrocatalysis oxidation in different operating conditions. The anode with high catalytic activity was selected from three kind of mixed metal oxide (MMO) coated Ti-based electrodes, and the reaction parameters were determined. The experiments of brief reversing electrode operation were carried out to investigate the descaling effect and the influence on the water quality, and the operation mode was determined. Research shows that CRR/EC of Ti-based electrodes modified by Ru+Ir mixed metal oxide increases with the rise of pH value, higher than that modified by Pt+Ir mixed metal oxide when pH>5. The CRR/EC of Ti-based electrodes modified by Ta+Ir mixed metal oxide is lower than that modified by Pt+Ir or Ru+Ir mixed metal oxide under different pH conditions. Ti-based electrodes modified by Pt+Ir mixed metal oxide was screened out and pH of 7, plate distance of 1 cm, current intensity of 8.64 mA/cm ², electrolysis time of 30 min were taken as the optimum conditions. Under the optimum conditions, the CRR can reach 31.9%, CRR/EC is 3.68%/(kW·h/t), and energy consumption is 8.66 kW·h/t. The operation mode is set at the cycle reaction of that reverses 5-10 min after every 30-60 min.