Abstract: During the harmless disposal of diseased dead animal, the secondary pollution could be generated from the separation of the cutting and mixing processes. Aiming at this problem, in combination with the characteristics of the shredder and the feed mixer, a kind of cutting blade that could simultaneously complete the functions of cutting and mixing was designed. By analyzing the cutting principle, the cutting-line was deviated from the rotation center to achieve the “sliding cut” effect. The blade was designed with circular arc to improve the distribution of stress, and the blade length was increased to make the cutting more stable. The optimal mixing angle between the switch plate and the cutting blade was determined to be 70° by single factor experiment. The equipment adopts the indirect heating heat transfer oil, which has the advantages of high stability and good heat transfer. Through the theoretical calculation, the motor power of the equipment was selected at 3 kW, with the rated speed of 1 440 r/min. The helical gear reducer was selected for reducer with the speed ratio of 1 000. The pilot test showed that the blade could basically complete the function of cutting and mixing. It needed about 20 h to heat up the material and main the temperature at over 90 ℃, while the temperature fluctuation was obvious within 10-20 h. The test result of pestivirus suis, etc. for the disposed products were all negative, showing that harmless disposal had been achieved. The moisture content of the product is 23%, with pH 5.7, seed germination rate 80%, total nitrogen 3.1% and total phosphorus 2.1%, all achieving the requirement of Organic Fertilizer Standard (NY 525-2012).