Abstract: Canada has set up a management system with complete legislation, rigorous methods and abundant means in chemical management. It has formed a three-level management system framework of federal, provincial and municipal levels, with rigorous management as the basic principle, life cycle management as its characteristic and multi-sectoral coordination as an important approach. The experience should be important reference for improving China’s chemical management. The legislation of chemicals management in Canada and the chemical management programs were reviewed, emphatically the management ideas of Canadian Environmental Protection Law, Hazardous Product Act, Workplace Hazardous Materials Information System, and New Substances Notification Regulations were interpreted. The progress of chemicals management in China were summarized, and the proposals were put forward to perfect China’s chemicals management as follows: improving the legislation of chemical environmental management, establishing the life cycle management system for chemicals, strengthening risk control measures and establishing the priority control list, and encouraging public participation.