Abstract: Qicai Lake in Guiyang City was selected as a typical case of the treatment of black and odorous water body in karst landform area in south China, the main water environmental problems, treatment measures, typical treatment technologies and treatment effects were introduced. Qicai Lake was identified as heavy-level black and odorous water body before treatment, due to insufficient sewage collection capacity, random stacking of household garbage, serious sediment deposition and so on. In order to solve these problems, Guiyang City proposed governance strategies of source pollution control, pollution interception, internal source treatment, fresh water supply and circulation, ecological restoration, landscape building, and the integrated wastewater treatment technology based on sludge sediment grit oil (SSgo) solid-liquid quick separation technology and fluidized bed biological reactor (FBBR) in the tank, habitat creation and ecological restoration technology, and the living water cycle quality extraction technology were used to carry out the renovation. Good environmental, economic and social effects had been achieved after restoration of Qicai Lake.