群体感应调控有机污染物生物降解研究进展

余晓龙; 毛旭辉; 郑焰

doi:10.12153/j.issn.1674-991X.20230151

群体感应调控有机污染物生物降解研究进展

doi: 10.12153/j.issn.1674-991X.20230151

余晓龙^1,,
毛旭辉²,
郑焰^1, ,

1.
南方科技大学环境科学与工程学院
2.
武汉大学资源与环境科学学院

基金项目: 国家重点研发计划项目（2020YFC1807902）；广东省基础与应用基础研究基金项目（2021A1515110757）

详细信息

作者简介:
余晓龙(1988—)，男，副研究员，博士，主要从事污染物生物处理研究，yu.xiaolong@hotmail.com

通讯作者:
郑焰(1969—)，女，教授，博士，主要从事地球化学研究，yan.zheng@sustech.edu.cn

中图分类号: X703
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- HTML全文浏览量: 184
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- 被引次数: 0
出版历程
- 收稿日期: 2023-02-24

Research progress on quorum sensing regulation of organic pollutants biodegradation

YU Xiaolong^1
,,
MAO Xuhui²,
ZHENG Yan^{1
, ,}

1.
School of Environmental Science and Engineering, Southern University of Science and Technology
2.
School of Resource and Environmental Sciences, Wuhan University

摘要

摘要:
有机污染物的生物降解效果受微生物活性影响，群体感应是微生物控制其生理活性的重要机制。在有机污染物生物降解过程中，群体感应对关键降解酶的合成、生物膜的形成以及菌群结构的调控等产生影响。直接投加群体感应信号分子或能产生信号分子的菌剂可促进群体感应调控，提高污染物降解率，但pH、温度、群体感应淬灭菌、纳米颗粒物等环境因素可影响群体感应的活性。当前，群体感应调控有机污染物生物降解的研究尚处于起步阶段。综述了相关研究进展，介绍了群体感应对有机污染物生物降解的影响机理，归纳了强化群体感应调控的方式和影响群体感应活性的主要环境因素，并对其应用前景进行了展望。
- 群体感应 /
- 生物降解 /
- 多环芳烃（PAHs） /
- 信号分子 /
- 调控机制
Abstract:
The biodegradation of organic pollutants is influenced by microbial activities, and quorum sensing (QS) is a crucial mechanism that regulates physiological activities. During the biodegradation process of organic pollutants, QS affects the synthesis of key enzymes for degradation, the formation of biofilms, the regulation of microbial community structure, etc. Furthermore, directly adding QS signaling molecules or using bacterial agents that produce such molecules can promote QS regulation, thereby enhancing organic pollutants biodegradation rates. However, environmental factors like pH, temperature, quorum quenching bacteria, nanoparticles, etc., can negatively impact QS activities. Currently, research on QS regulation of organic pollutant biodegradation is still in its early stages. This review summarizes the progress of related research, discusses the mechanisms of QS on the biodegradation of organic pollutants, outlines strategies to enhance QS regulation, identifies the main environmental factors affecting QS activities, and provides prospects for its application.
- quorum sensing /
- biodegradation /
- polycyclic aromatic hydrocarbons (PAHs) /
- signaling molecules /
- regulation mechanism

HTML全文

图 1 革兰氏阴性菌、阳性菌使用的主要信号分子结构

Figure 1. Main signal molecular structures used by Gram-negative and Gram-positive bacteria

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图 2 QS调控机制示意

Figure 2. Scheme for QS regulation mechanism

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表 1 受AHL-QS调控的纯菌对有机污染物的降解研究

Table 1. Research on the biodegradation of organic pollutants by pure cultures regulated by AHL-QS

纯菌	产生的AHLs	有机污染物	QS调控作用
Pseudomonas aeruginosa PAO1^[16-17,19]	C4-HSL、3OC12-HSL	PAHs	调控生物膜形成、鼠李糖脂合成与分泌
Pseudomonas aeruginosa N6P6^[28]	C4-HSL、3OC12-HSL	PAHs	影响PAHs降解率和生物膜结构
Croceicoccus naphthovorans PQ-2^[29-30]	3OC6-HSL、3OH-C8-HSL	PAHs	调控降解酶的基因表达、细胞表面疏水性
Novosphingobium pentaromativorans US6-1^[31]	结构未明的AHLs	PAHs	调控降解酶的基因表达、细胞表面疏水性和EPS生成
Pseudomonas putida AQ8^[24]	中长链AHLs	BTEX	调控苯/甲苯双加氧酶基因和联二苯/甲苯/苯双加氧酶基因表达
Pseudomonas aeruginosa CGMCC 1.860^[25-26]	C4-HSL、C6-HSL	苯酚	调控双加氧酶合成
Sphingonomas sp. YK5^[27]	C8-HSL	双酚A	调控降解酶的基因表达
Acinetobacter sp. DR1^[32]	结构未明的AHLs	正十六烷	调控正十六烷降解和生物膜形成

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表 2 强化AHL-QS调控对混合微生物体系降解有机污染物的研究

Table 2. Research on the biodegradation of organic pollutants by mixed cultures enhanced by AHL-QS regulation

混合体系	QS强化手段	有机污染物	QS调控作用
活性污泥^[44]	投加C6-HSL和3OC6-HSL	苯酚	维持稳定的苯酚降解率
生物滤池^[46]	投加混合AHLs或接种QS菌	氯苯	降解率提升约50%，优化生物膜形成和菌群多样性
生物滤池^[47]	投加混合AHLs或接种QS菌	甲苯	促进了甲苯的溶解性和平均降解率，提高低温条件下附着生物量及生物膜分布的均一性
石油污染土壤^[45]	投加C12-HSL和烷烃降解混合菌	烷烃	提高碳氢化合物的降解率，促进混合菌生物膜形成，强化微生物呼吸作用活性
微生物燃料电池^[48]	投加从EPS中提取的AHLs	氯霉素	加快氯霉素的降解，促进生物膜形成，维持稳定电流输出
功能性菌群^[37]	投加含形成生物膜的QS菌	造纸废水	强化生物膜形成，提高木质素的降解率

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