Analysis of research hotspots on antibiotics and endocrine disruptors in rivers based on bibliometrics
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摘要:
抗生素与内分泌干扰物是近些年全球广泛关注的新污染物。基于中国知网和Web of Science数据库检索河流中抗生素与内分泌干扰物环境行为的研究动态，使用CiteSpace和VOSviewer软件进行文献计量学分析。结果表明：2000—2022年共发表该研究领域相关文献2 085篇，包括399篇中文和1 686篇英文文献，年发文量呈上升趋势且在过去5年迅速增长。英文文献涉及全球96个国家和2 022所研究机构，中国和美国的国际表现力较为突出，发文量分别为773和251篇，其中中国科学院大学发文量位居第一且与国内外机构合作紧密。发文的期刊以环境科学类为主，多学科交叉融合，其中中英文期刊分别以《环境科学》和Science of the Total Environment发文量最多。关键词聚类与时区图谱表明，该领域当前以区域性研究为主，双酚A、壬基酚、有机氯农药等内分泌干扰物与四环素类、磺胺类、喹诺酮类等抗生素在河流中的污染特征研究较为广泛，而针对激素类内分泌干扰物的研究仍不充分，污染物在河流中的迁移、转化、去除等机理研究是当前主要方向。突现词结果表明，过去20年该领域研究可分为3个阶段，早期研究以分析方法和河流中赋存特征等污染调查为主，中期研究以探究污染物的运移归趋为主，近年来研究由生态风险评估转向河流水生态健康管理服务，发展符合区域特征的污染物管控策略与去除技术是当前热点和未来趋势。此外，由抗生素污染衍生的耐药性问题引起全球关注，抗生素抗性基因的产生和传播机制及生态与健康风险也是当前热点和未来关注的重点。
Abstract:Antibiotics and endocrine disruptors are emerging contaminants that have attracted global attention in recent years. Based on the databases of China National Knowledge Infrastructure (CNKI) and Web of Science (WoS), relevant literature on the environmental behavior of antibiotics and endocrine disruptors in rivers was retrieved. CiteSpace and VOSviewer software were used for bibliometric analysis and visualization display. The results showed that a total of 2 085 relevant papers were searched in CNKI and WoS from 2000 to 2022, including 399 Chinese articles and 1 686 English articles. The research in this field showed an upward trend and increased rapidly in the past five years. The English literature involved 96 countries and 2 022 institutions, and the international performance of China and the United States was the most prominent, with 773 and 251 articles published respectively. The University of Chinese Academy of Sciences ranked first in publications and cooperated closely with institutions at home and abroad. The journals published were mainly in the field of environmental science with interdisciplinary integration, with Environmental Science (Chinese) and Science of the Total Environment topping the publications. The keywords clustering and time zone maps showed that regional research was mainly focused at present. The pollution characteristics of endocrine disruptors including bisphenol A, nonylphenol and organochlorine pesticides, and antibiotics including sulfonamides, tetracyclines and quinolones in rivers were most widely studied, while research on hormonal endocrine disruptors was still insufficient. Study on the migration, transformation and removal mechanisms of the pollutants in rivers was the main trend. The results of keywords of strongest citation bursts indicated that the research in this field over the past 20 years could be divided into three stages. In the early stage, research mainly focused on analysis methods and investigation on the occurrence and characteristics of the contaminants in rivers. In the mid-term, studies primarily concentrated on examining the contaminant transport and fate. In recent years, it has shifted from ecological risk assessment to river water ecological health management services, and the development of pollution control strategies and removal technologies based on regional characteristics are current hotspots and future trends. Besides, the issue of antibiotic resistance originating from antibiotic contamination has garnered global attention, and the generation and transmission mechanism of antibiotic resistance genes and their ecological and health risk are also current hotspots and possible future focus.
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Key words:
- antibiotics /
- endocrine disruptors /
- river /
- environmental behavior /
- bibliometrics /
- visual analysis
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图 2 2000—2022年主要发文国家（地区）及合作关系
Figure 2. Publication countries (region) and their cooperation from 2000 to 2022
图 3 2000—2022年CNKI和WoS发文研究机构合作共现图谱
Figure 3. Network of institutional cooperation based on CNKI and WoS data from 2000 to 2022
图 4 2000—2022年CNKI文献学科类别分布
Figure 4. Distribution of subject category of CNKI publications from 2000 to 2022
图 5 2000—2022年WoS期刊双图叠加知识图谱
Figure 5. Knowledge map of periodical double graph superposition for WoS publications from 2000 to 2022
图 6 2000—2022年CNKI和WoS中文献关键词时区图
Figure 6. Keywords time zone map for CNKI and WoS publications from 2000 to 2022
图 7 2000—2022年 CNKI和WoS文献关键词共现谱图
Figure 7. Network of keywords coexistence based on CNKI and WoS data from 2000 to 2022
表 1 2000—2022年发文量排名前10的期刊
Table 1. Top 10 journals with publication amount from 2000 to 2022
序号 CNKI WoS 期刊 影响因子 发文量/篇 占比/% 期刊 影响因子 发文量/篇 占比/% 1 《环境科学》 4.074 13 3.26 Science of the Total Environment 9.8 278 16.49 2 《中国环境科学》 2.483 10 2.51 Environmental Science and Pollution Research 5.8 108 6.41 3 《环境化学》 1.565 8 2.01 Chemosphere 8.8 106 6.29 4 《环境科学学报》 2.333 8 2.01 Environmental Pollution 8.9 98 5.81 5 《土壤》 2.243 6 1.50 Water Research 12.8 58 3.44 6 《农业环境科学学报》 2.367 6 1.50 Journal of Hazardous Materials 13.6 50 2.97 7 《环境科学与技术》 1.130 6 1.50 Environmental Science Technology 11.4 43 2.55 8 《净水技术》 0.875 5 1.25 Marine Pollution Bulletin 5.8 42 2.49 9 《环境工程技术学报》 2.572 3 0.75 Environment International 11.8 40 2.37 10 《安徽农业科学》 0.596 3 0.75 Ecotoxicology and Environmental Safety 6.8 38 2.25 
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表 2 2000—2022年CNKI文献突现强度排名前25的关键词
Table 2. Top 25 keywords with the strongest citation bursts based on CNKI data from 2000 to 2022
关键词 强度
（Strength）突变开始
（Begin）突变结束
（End）突现图谱（2001—2022年） 内分泌干扰物 4.30 2001 2014 
双酚A 5.02 2005 2013 壬基酚 3.42 2005 2013 生物降解 3.59 2006 2009 固相萃取 2.79 2009 2018 降解 2.85 2011 2017 地下水回灌 1.60 2012 2015 四环素 1.91 2013 2017 生态风险 1.87 2014 2015 兽用抗生素 1.73 2014 2018 土霉素 2.22 2015 2017 水环境 1.80 2015 2017 迁移转化 1.60 2016 2017 磺胺类抗生素 3.20 2017 2019 生物炭 1.80 2017 2018 多介质 1.31 2017 2019 抗性基因 2.51 2018 2019 风险评价 1.86 2018 2022 磺胺嘧啶 1.63 2018 2020 抗生素抗性基因 9.60 2019 2022 微生物群落 3.15 2019 2022 紫色土 3.06 2019 2020 微塑料 2.92 2019 2022 风险评估 2.22 2020 2022 畜禽粪污 1.82 2020 2022
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表 3 2000—2022年WoS文献突现强度排名前25的关键词
Table 3. Top 25 keywords with the strongest citation bursts based on WOS data from 2000 to 2022
关键词 强度（Strength） 突变开始年（Begin） 突变结束（End） 突现图谱（2000—2022年） antibacterial agent 7.12 2000 2017 
endocrine disruptor 18.27 2001 2012 alkylphenol 7.09 2001 2013 sewage treatment plant 6.28 2002 2013 pharmaceutical 9.25 2003 2012 oxytetracycline 10.12 2004 2017 liquid chromatography 7.64 2004 2014 behavior 5.20 2004 2012 solid phase extraction 5.19 2004 2014 solid phase extraction 21.61 2005 2014 tandem mass spectrometry 16.81 2006 2014 trimethoprim 6.21 2008 2015 sewage 6.25 2009 2015 estrogen 5.93 2010 2015 tetracycline resistance 5.65 2010 2018 river discharge 5.94 2012 2018 south China 14.38 2013 2018 drug 5.28 2014 2015 wastewater treatment 5.30 2016 2018 ARGs 7.41 2019 2020 spatiotemporal distribution 5.37 2019 2022 impact 7.31 2020 2022 pollution 6.22 2020 2022 ecological risk 5.88 2020 2022 microbial community 5.82 2020 2022
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